Medicare Thailand

ICSI- intracytoplasmic sperm injection with IVF is a highly effective fertility treatment for male factor infertility and sperm defects.

An insight into the ICSI process. 

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ICSI Process:

What is ICSI?

ICSI is an acronym for intracytoplasmic sperm injection - which is a long, fancy way of saying "inject sperm into the middle of the egg". ICSI is a very effective method to get fertilization of eggs in the IVF lab after they have been retrieved from the female partner. IVF with ICSI involves the use of specialized tools and inverted microscopes that enable embryologists to select and then pick up individual sperms in a tiny specially designed hollow ICSI needle. Then the needle is carefully advanced through the outer shell of the egg and egg membrane and the sperm is then injected into the inner part (cytoplasm) of the egg.  This will usually result in normal fertilization in approximately 70-85% of eggs injected with viable sperm. First, the woman must be stimulated with medications and have an egg retrieval so that we can obtain several eggs in order to attempt in vitro fertilization and ICSI.

Who should be treated with intracytoplasmic sperm injection?

1. All couples with severe male factor infertility that do not want donor sperm insemination.

2. All couples with infertility with:

Sperm concentrations of less than 15-20 million per milliliter
OR
Sperm motility less than 35%
OR
Very poor sperm morphology (subjective - specific cutoff value is not appropriate)

3. All couples having IVF who have had a previous cycle with no fertilization - or a low rate of fertilization (low percentage of mature eggs that are normally fertilized).

4. All couples having IVF who have a very low yield of eggs at the egg retrieval - our current cutoff is 5-6 (or less) eggs. In this scenario, ICSI is being used to try to get a higher percentage of eggs fertilized than with conventional insemination of the eggs (just mixing eggs and sperm together).

How is ICSI performed?

1. The mature egg is held with a specialized holding pipette.

2. A very delicate, sharp and hollow needle is used to immobilize and pick up a single sperm.

3. This needle is then carefully inserted through the zona(shell of the egg) and in to the cytoplasm of the egg.

4. The sperm is injected in to the cytoplasm and the needle carefully removed.

5. The eggs are checked the next morning for evidence of normal fertilization..

Treatment Cost of treatment
(ThB)

 IVF 164,000

 ICSI 184,000(includes IVF)

 PGD for aneuploidy screening 80,000

 PGD for single gene disorder 150,000

 PGD for translocation 150,000

 Frozen ET 30,000

Included:

• ovarian stimulation
• egg pick up (OPU)
• sperm preparation
• embryo culture to blastocyst stage
• embryo transfer
• doctor's fee
• standard medication in long protocol
• hormone and blood tests
• ultrasound
• monitoring
• anesthesia
• operation theater

There is an option for PGD to screen for any conditions the embryo might have or this can also be used as a family planing choice. For more details please request.